Guardians-Rays ALCS odds: Best player prop bets for Game 6

The Tampa Bay Rays are up 3-2 on the Cleveland Guardians as they host Game 6 of the ALCS. They secured a 3-1 victory in Game 5 and now have a chance to advance to the World Series.

>First pitch is set 8:08 PM ET at Tropicana Field. You can watch Game 6 on TBS and TruTv.

>Shawn Armstrong will start for the Guardians, and Freddy Peralta will start for the Rays. This series has had all the emotions and drama you would expect from an ALCS. It should be no different tonight.

>Here are the three best player prop bets for this critical game.

>MORE: Guardians reveal their pitching plans for ALCS Game 6

José Ramírez to record a hit (-183 at DraftKings)Oct 15, 2026; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) reacts after being caught stealing second base against the Tampa Bay Rays during the first inning in game three of the ALCS for the 2026 MLB Playoffs at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesIf the Guardians want to force a Game 7, they’ll need a big-time performance from José Ramírez. He has recorded a hit in four of his last six MLB postseason games. Ramírez tallied a single in their Game 5 loss.

JOSÉ RAMÍREZ!

GUARDIANS TAKE THE FIRST LEAD OF GAME 5! pic.twitter.com/Z0zoqm513R

— MLB (@MLB) October 11, 2026He had a single off of Peralta in Game 1 of this series and will be fired up to extend this to a deciding Game 7. The third baseman recorded 111 hits during the regular season, 39 of which were extra-base hits.

>MORE: Rays announce pitching plans with World Series berth on the line

Freddy Peralta under 4.5 strikeouts (-164 at DraftKings)Sep 1, 2026; St. Petersburg, Florida, USA; Tampa Bay Rays starting pitcher Freddy Peralta (51) throws a pitch during the sixth inning against the New York Mets at Tropicana Field. Mandatory Credit: Kim Klement Neitzel-Imagn ImagesThe Rays are sending Freddy Peralta to the mound, and it could be a short outing for the righty. He has struck out four or fewer batters in three of his last four starts. Peralta didn’t record a strikeout in a short Game 4 outing.

>He’s only on two days’ rest, so the leash could be short in this massive game. If the Guardians want to do some damage, they’ll have to get Peralta out of the game early.

Yandy Diaz over 1.5 Hits + Runs + RBIs (-121 at DraftKings)Oct 15, 2026; Cleveland, Ohio, USA; Tampa Bay Rays designated hitter Yandy Diaz (2) hits a double during the fourth inning against the Cleveland Guardians at Progressive Field. Mandatory Credit: David Richard-Imagn ImagesYandy Diaz has been a beast for the Rays this playoff run. He collected three hits in Game 5, including a double to lead off the game.

YANDY DÍAZ BREAKS THIS GAME OPEN 🤯

It's a 2-run shot that just gets over the wall 😮 pic.twitter.com/82aJnxo9Al

— MLB (@MLB) October 18, 2026Diaz has produced over 1.5 Hits + Runs + RBIs in three of the last four postseason games. The designated hitter contributed 41 hits, 16 RBIs, and 16 runs scored in 34 career games against Cleveland.